Teriparatide: 5-10mg*10 vials

Product Description: Teriparatide

Introduction:
Teriparatide is a synthetic peptide that represents the active fragment of parathyroid hormone (PTH), a naturally occurring hormone produced by the parathyroid glands. It is primarily used in scientific research to investigate bone metabolism, bone regeneration, and cellular activities related to bone remodeling. Teriparatide is a critical research tool in the field of osteology and regenerative medicine. This peptide is often explored in studies focused on the regulation of bone formation, osteoblast activity, and the signaling pathways involved in bone cell differentiation.

What is Teriparatide?
Teriparatide is a recombinant peptide consisting of the first 34 amino acids of the parathyroid hormone, PTH. The fragment mimics the biologically active portion of the hormone, which is responsible for regulating calcium and phosphate balance in the body, as well as influencing bone remodeling and growth. Teriparatide, as a truncated form of PTH, specifically promotes the activity of osteoblasts, the cells responsible for bone formation.

The peptide is commonly used in research to study the effects of parathyroid hormone signaling on bone metabolism, bone health, and bone regeneration. While Teriparatide has potential applications in the study of bone diseases and disorders, it is essential to note that this peptide is intended solely for research purposes and not for human consumption.

Potential Different Names:

• Teriparatide
• Recombinant PTH (1-34)
• PTH fragment
• Parathyroid hormone fragment
• PTH 1-34
• Forteo (brand name in certain applications)

Chemical Formula:
The chemical formula for Teriparatide is C153H240N44O48S. This formula represents the molecular composition of the peptide, which is derived from the first 34 amino acids of the natural parathyroid hormone.

Structure:
Teriparatide consists of a chain of 34 amino acids. The structure of the peptide includes a specific sequence that mirrors the active portion of the parathyroid hormone. This sequence allows Teriparatide to interact with the parathyroid hormone receptor (PTH1R), which is involved in regulating key processes in bone metabolism. The specific sequence of amino acids in Teriparatide enables it to modulate osteoblast activity and bone remodeling, promoting bone formation under certain conditions. The peptide is typically synthesized through recombinant DNA technology, ensuring high purity and consistency in the resulting product.

How Does It Work?
Teriparatide works by binding to and activating the PTH1 receptor, which is found on the surface of osteoblasts and other bone cells. The activation of this receptor triggers a series of intracellular signaling pathways that influence bone formation and remodeling.

One of the primary mechanisms of Teriparatide's action is the stimulation of osteoblast differentiation and activity. Osteoblasts are responsible for synthesizing bone matrix proteins, such as collagen, which are essential for bone structure and integrity. By promoting the activity of osteoblasts, Teriparatide encourages bone formation.

In addition to its effects on osteoblasts, Teriparatide may also influence the activity of osteoclasts, the cells responsible for the resorption or breakdown of bone tissue. This balance between osteoblast and osteoclast activity is crucial for maintaining bone homeostasis. The exact effects of Teriparatide on osteoclasts are still being explored in scientific research, as they may depend on various factors, including the duration of exposure and the specific conditions of the study.

Teriparatide is primarily used in laboratory settings to investigate bone biology, bone regeneration, and disorders related to bone density and metabolism. It is often utilized in studies exploring osteoporosis, fracture healing, and bone tissue engineering.

Conclusion:
Teriparatide is a synthetic peptide derived from the first 34 amino acids of parathyroid hormone. It is used primarily in research to study the regulation of bone formation, bone metabolism, and cellular processes related to bone remodeling. By activating the PTH1 receptor, Teriparatide promotes osteoblast activity and may influence bone regeneration and growth. Its applications in bone research, particularly in the study of osteology and regenerative medicine, make it a valuable tool in understanding bone health and disease. However, it is important to note that Teriparatide is intended for research purposes only and should be handled by professionals in controlled laboratory environments.

Disclaimer:
This product description is for informational purposes only and is intended solely for research use in laboratory settings. Teriparatide is not intended for human consumption or clinical use. It should be used only by qualified researchers in compliance with all relevant regulations, safety guidelines, and ethical standards. The peptide is for research purposes only and is not approved for use in humans. Always ensure that research with Teriparatide adheres to institutional and governmental guidelines.