Product Description: PT-141
Introduction:
PT-141, also known as Bremelanotide, is a synthetic peptide that has gained attention in research fields, particularly those focused on neurobiology and physiology. It is a potent peptide that acts on melanocortin receptors, and researchers study its mechanisms to better understand its interactions in various biological systems. PT-141 is synthesized with high-quality standards for use in controlled laboratory experiments, offering a valuable tool for scientists to explore its effects in neuroendocrine and behavioral studies.
What is PT-141?
PT-141 is a peptide analogue of the naturally occurring hormone alpha-melanocyte-stimulating hormone (α-MSH). It is primarily studied for its ability to interact with specific melanocortin receptors in the body, particularly the melanocortin receptors 3 and 4 (MC3R and MC4R). PT-141 has been used extensively in preclinical research to examine its effects on various biological functions, especially those related to central nervous system activity and hormone regulation. Unlike other peptides in its class, PT-141 does not primarily target the skin (as α-MSH does), making it of particular interest for researchers in the fields of neurochemistry and endocrinology.
Potential Different Names:
- Bremelanotide
- PT-141 Peptide
- Melanotan II analogue
Chemical Formula:
The chemical formula for PT-141 (Bremelanotide) is C14H19N5O3. This formula represents the molecular composition of the peptide, which consists of carbon (C), hydrogen (H), nitrogen (N), and oxygen (O). The molecular structure is designed to allow it to interact with melanocortin receptors, which are involved in a range of physiological functions.
Structure:
PT-141 is a synthetic peptide composed of 7 amino acids. Its sequence is as follows:
- Ac-Nle-cyclo(ASP-His-DPhe-Arg-Trp)NH2
This sequence contains modified amino acids, including D-phenylalanine (DPhe), which give PT-141 its specific biological activity. The cyclic structure and the incorporation of D-amino acids enhance its stability and receptor binding affinity, making it an interesting compound for research purposes.
How Does It Work?
PT-141 functions by binding to melanocortin receptors, primarily MC3R and MC4R, which are located in the central nervous system. These receptors play roles in various physiological processes, including those related to appetite, sexual function, and energy regulation. PT-141’s ability to bind to these receptors is studied in relation to its potential effects on behaviors regulated by the brain, such as motivation, arousal, and more. Unlike other melanocortin receptor agonists, PT-141 does not directly influence pigmentation, which makes it a distinct compound of interest for neurobiological research.
By activating these receptors, PT-141 can modulate different pathways and responses within the central nervous system, although the exact mechanisms are still being investigated in scientific settings. Researchers use PT-141 to explore its effects in a variety of models, helping to deepen understanding of how the melanocortin system interacts with other hormonal and neural pathways in the body.
Conclusion:
PT-141 is a synthetic peptide that acts as a melanocortin receptor agonist, primarily interacting with MC3R and MC4R receptors in the central nervous system. It is used in scientific research to study its effects on neural and hormonal systems, particularly in relation to behaviors and processes regulated by these receptors. PT-141’s structure and activity offer a unique opportunity for exploring the complex interactions of the melanocortin system in various physiological contexts.
Disclaimer:
This product description is for informational purposes only and is intended for laboratory research use only. PT-141 is not for human consumption and should be handled by qualified professionals in a controlled research environment. The information provided does not make any health claims and should not be used as a basis for clinical use. Researchers should ensure that they comply with all applicable regulations and safety guidelines when handling this product.