Octreotide: 5-10mg*10 vials

Product Description: Octreotide

Introduction
Octreotide is a synthetic analogue of somatostatin, a naturally occurring peptide hormone that inhibits the release of various other hormones in the body. It is commonly used in research settings to investigate its biochemical properties, mechanism of action, and potential applications in various fields of science. This product, available in a high-purity form, allows researchers to study the effects of Octreotide in cellular, molecular, and biochemical processes. It is specifically designed for laboratory research and scientific inquiry.

What is Octreotide?
Octreotide is a synthetic version of the naturally occurring hormone somatostatin. It is a cyclic octapeptide, meaning it consists of eight amino acids, which mimic the structure and function of somatostatin. Octreotide’s main role in the body is to inhibit the secretion of several hormones and peptides, including growth hormone, insulin, and glucagon. By studying its interactions and functions, scientists can gain valuable insights into the regulation of hormonal systems and their applications in various research areas.

Potential Different Names

• Sandostatin (brand name)
• Octreotide acetate
• Somatostatin analogue
• Octreotide acetate injection
• Somatostatin 28-47 analogue

Chemical Formula
The chemical formula for Octreotide is C49H66N10O10S2.

Structure
Octreotide is a cyclic peptide composed of eight amino acids. Its structure is derived from somatostatin but with modifications to improve its stability and potency. The modified structure of Octreotide involves the introduction of D-amino acids at specific positions in the peptide chain, allowing for a longer half-life and increased resistance to enzymatic degradation. The cyclic nature of Octreotide’s structure is essential for its ability to bind to somatostatin receptors and exert its physiological effects.

The key elements of its structure include:

• A cyclic arrangement of eight amino acids
• A thiazolidine ring that contributes to its stability
• A disulfide bond that stabilizes the peptide chain

This modified structure enables Octreotide to interact with somatostatin receptors, particularly type 2 and type 5, and modulate the secretion of certain hormones.

How Does it Work?
Octreotide works by mimicking the effects of somatostatin, inhibiting the release of several important hormones. It primarily exerts its effects through binding to somatostatin receptors, which are present on the surface of various cells throughout the body. By interacting with these receptors, Octreotide prevents the release of certain hormones, such as growth hormone, insulin, glucagon, and gastrointestinal peptides.

Its mechanism of action involves:

• Binding to somatostatin receptors: Octreotide binds to specific receptors located on cells in the pituitary gland, pancreas, and gastrointestinal system.
• Inhibition of hormone release: Upon receptor binding, Octreotide suppresses the secretion of various hormones, including growth hormone, insulin, glucagon, and certain gastrointestinal peptides. This leads to a reduction in the activity of these hormones.
• Longer half-life: Unlike somatostatin, which has a very short half-life, Octreotide has been engineered to be more stable in the bloodstream, allowing it to exert its effects for a longer duration.

Researchers use Octreotide in studies to explore the role of somatostatin and its analogues in regulating hormone secretion, endocrine function, and various cellular pathways.

Conclusion
Octreotide is a synthetic analogue of somatostatin, designed for research purposes to explore its role in inhibiting hormone release and regulating endocrine and cellular functions. Its cyclic structure and receptor binding properties make it a valuable tool in investigating hormonal regulation, endocrine signaling, and peptide interactions in biological systems. This high-purity product offers researchers the opportunity to further study the complex mechanisms by which Octreotide exerts its effects in the body.

Disclaimer
Octreotide is intended for research purposes only and is not for human consumption or clinical use. It should only be used by qualified professionals in a controlled laboratory setting. The information provided here is for scientific and educational purposes only and does not make any health claims regarding the use of this product. Always follow proper safety protocols and guidelines when handling and storing this product.