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Nexus Peptides

Humanin: 5-10mg*10 vials

Humanin: 5-10mg*10 vials

Regular price $189.99 USD
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Introduction: Humanin is a small peptide that was first discovered in 2001. It is a part of the mitochondrial genome and is known for its potential cytoprotective effects, including anti-apoptotic properties.

What is Humanin? Humanin, also known as MAPRGFSCLLLLTSEIDLPVKRRA, is a 24-amino acid peptide that is encoded within the mitochondrial DNA. It is involved in various cellular processes, particularly those related to cell survival and apoptosis inhibition.

Potential Different Names:

  • MAPRGFSCLLLLTSEIDLPVKRRA (amino acid sequence)
  • MAPRGF (short form)
  • Mitochondrial-derived peptide Humanin (MDP)

Chemical Formula: The chemical formula of Humanin is C130H204N40O41, reflecting its composition of carbon, hydrogen, nitrogen, and oxygen atoms.

Structure: Humanin adopts a unique three-dimensional structure that is crucial for its biological activity. It contains an alpha-helical region that allows it to interact with cellular receptors and exert its cytoprotective effects.

How Does it Work? Humanin primarily acts through interaction with specific cell surface receptors, including the insulin-like growth factor-1 receptor (IGF-1R) and the pro-apoptotic BAX protein. By binding to these receptors, Humanin can activate intracellular signaling pathways that promote cell survival and inhibit apoptosis.

Potential Applications:

  • Neuroprotection: Humanin has shown promising results in preclinical studies for the treatment of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease.
  • Cardiovascular health: Humanin may have cardioprotective effects and could be explored as a therapeutic agent for the prevention and treatment of cardiovascular diseases.
  • Anti-aging: Some research suggests that Humanin may play a role in modulating the aging process and could be investigated as a potential anti-aging intervention.
  • Metabolic disorders: Humanin has been studied for its potential role in regulating metabolism and glucose homeostasis, offering potential applications in the management of metabolic disorders, such as diabetes.

Potential Side Effects:

  • Limited information is available regarding the potential side effects of Humanin.
  • Further research is needed to assess its safety profile, particularly in clinical settings.

Dosage: Dosage recommendations for Humanin have not been established, as it is primarily studied in preclinical models. Clinical trials are needed to determine optimal dosing regimens for therapeutic use in humans.

What to Check Before: Before considering Humanin therapy, individuals should:

  • Consult with a healthcare professional to discuss potential risks and benefits.
  • Ensure that they do not have any underlying medical conditions or contraindications that may impact the safety or efficacy of Humanin treatment.
  • Stay informed about the latest research developments and clinical trials involving Humanin.

Conclusion: Humanin is a promising peptide with potential applications in various fields, including neuroprotection, cardiovascular health, anti-aging, and metabolic disorders. While preclinical studies have provided encouraging results, further research is needed to elucidate its mechanisms of action and evaluate its safety and efficacy in clinical settings.

Disclaimer: Humanin is currently under investigation for research purposes only and is not approved for clinical use. This product description is for informational purposes only and should not be construed as medical advice. Individuals should consult with a qualified healthcare professional before considering Humanin therapy.